ClinicalTrials.gov Identifier: NCT06347978

We are conducting a research study into personalized deep brain stimulation (DBS) for Obsessive-Compulsive disorder (OCD) at the University of California, San Francisco (UCSF), which will be guided by invasive brain mapping.

We are looking for a total of 10 adult patients with treatment-refractory OCD.

If you are eligible and choose to be in this study, there will be three stages, including invasive brain mapping, placement of a 4-lead DBS system, and a randomized trial to determine the therapeutic effects of DBS On compared to DBS Off. Stage 3 will be followed by open label stimulation for an additional 6 months.

The total duration of the study is about 36 months. You should expect to be followed for up to 6 months beyond this point.

The purpose of this study is to determine if personalized deep brain stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes. The information we obtain in this study will be used to better understand the parts of the brain involved in Obsessive Compulsive Disorder (OCD). This study is led by Drs. A Moses Lee and Andrew Krystal.

Please email [email protected] if you are interested in participating or have any questions about the study.

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